Ageing PSA incorporating effectiveness of maintenance and testing

This paper proposes a new approach to Ageing Probabilistic Safety Assessment (APSA) modelling, which is intended to be used to support risk-informed decisions on the effectiveness of maintenance management programs and technical specification requirements of critical equipment of Nuclear Power Plants (NPP) within the framework of the Risk Informed Decision Making according to R.G. 1.174 principles. This approach focuses on the incorporation of not only equipment ageing but also effectiveness of maintenance and efficiency of surveillance testing explicitly into APSA models and data. An example of application is presented, which centres on a critical safety-related equipment of a NPP in order to evaluate the risk impact of considering different approaches to APSA and the combined effect of equipment ageing and maintenance and testing alternatives along NPP design life. The risk impact of the several alternatives is quantified and the results shows that such risk depends largely on the model parameters, such as ageing factor, maintenance effectiveness, test efficiency.Authors are grateful to the Spanish Ministry of Science and Innovation for the financial support of this work (Research Project ENE2013-45540-R) and the Doctoral Fellow (BES-2011-043906).Martón Lluch, I.; Sánchez Galdón, AI.; Martorell Alsina, SS. (2015). Ageing PSA incorporating effectiveness of maintenance and testing. Reliability Engineering and System Safety. 139:131-140. https://doi.org/10.1016/j.ress.2015.03.022S13114013

RELAP5 Simulation of PKL Facility Experiments under Midloop Conditions

Nuclear power plant risk has to be quantified in full power and in other modes of operation. This latter situation corresponds to low power and shutdown modes of operation in which the residual heat removal (RHR) system is required to extract the heat generated in the core. These accidental sequences are great contributors to the total plant risk. Thus, it is important to analyze the plant behavior to establish the accident mitigation measures required. In this way, PKL facility experimental series were undertaken to analyze the plant behavior in other modes of operation when the RHR is lost. In these experiments, the plant configurations were changed to analyze the influence of steam generators secondary side configurations, the temperature inside the pressurizer, and the inventory level on the plant behavior. Moreover, different accident management measures were proposed in each experiment to reach the conditions to restart the RHR. To understand the physical phenomena that takes place inside the reactor, the experiments are simulated with thermal-hydraulic codes, and this makes it possible to analyze the code capabilities to predict the plant behavior. This work presents the simulation results of four experiments included in PKL experimental series obtained using RELAP5/Mod3.3

An approach to address probabilistic assumptions on the availability of safety systems for deterministic safety analysis

[EN] There is an attempt nowadays to provide a more comprehensive and realistic safety assessment of design and operation of Nuclear Power Plants. In this context, innovative approaches are being proposed for safety assessment of nuclear power plants design including both design basis conditions and design extension conditions. An area of research aims at developing methods for combining insights from probabilistic and deterministic safety analyses in Option 4, also called realistic approach, from the International Atomic Energy Agency specific safety guide. The development of Option 4 or realistic approach involves the adoption of best estimate computer codes, best estimate assumptions on systems availability and best estimate of initial and boundary conditions for the safety analysis. This paper focusses on providing the fundamentals and practical implementation of an approach to integrate PSA-based probabilistic models and data, which incorporate best estimate assumptions on the availability of safety systems, into Option 4. It is presented a practical approach to identify relevant, i.e. most probable, configurations of safety systems and to assess the associated occurrence probability of each configuration using PSA models and data of a NPP, which is based on the use of a Pure Monte Carlo method. An example of application is provided to demonstrate how this approach performs. The case study focusses on an accident scenario corresponding to the initiating event Loss Of Feed Water (LOFW) for a typical three-loops Pressurized Water Reactor (PWR) NPP.Authors are grateful to the Spanish CSN (Consejo de Seguridad Nuclear) for the financial support of this research (Research Project SIN/4078/2013/640; MASA Project).Martorell Alsina, SS.; Martorell-Aygues, P.; Martón Lluch, I.; Sánchez Galdón, AI.; Carlos Alberola, S. (2017). An approach to address probabilistic assumptions on the availability of safety systems for deterministic safety analysis. Reliability Engineering & System Safety. 160:136-150. https://doi.org/10.1016/j.ress.2016.12.009S13615016

Differences in tetracycline resistance determinant carriage among Shigella flexneri and Shigella sonnei are not related to different plasmid Inc-type carriage

Objectives: The aim of this study was to establish the prevalence of the most common molecular mechanisms involved in tetracycline resistance as well as their relationship with plasmid incompatibility (Inc) groups in a collection of Shigella spp. causing traveller’s diarrhoea. Methods: Tetracycline susceptibility was established in 187 Shigella spp. (74 Shigella flexneri and 113 Shigella sonnei), of which 153 isolates were recovered as a confirmed cause of traveller’s diarrhoea. The prevalence of the tet(A), tet(B) and tet(G) genes was analysed by PCR. Eighteen plasmid Inc groups was determined in a subset of 59 isolates. Results: Among 154 tetracycline-resistant isolates, 122 (79.2%) harboured at least tet(A) or tet(B). The tet(B) gene was the most frequently detected, being present in 70 isolates (45.5%), whilst tet(A) was detected in 57 isolates (37.0%). The tet(G) gene was present in only 11 (7.2%) isolates. Moreover, the tet(A) gene was more frequent in S. sonnei (P = 0.0007), whilst the tet(B) gene was more frequent in S. flexneri (P < 0.0001). Plasmids belonging to Inc group B (P < 0.05) were significantly more frequent among S. flexneri, whilst those belonging to groups K, FIC and FIIA (P < 0.05) were preferentially detected among S. sonnei. Conclusion: The prevalence of the tet(A) and tet(B) genes differed between S. sonnei and S. flexneri. Moreover, the prevalence of plasmid Inc groups in S. flexneri and S. sonnei differed. However, no relationship was found between the two phenomena

Blind wideband source separation

This paper deals with the general problem of separating two independent wideband sources when they are mixed by unknown filters. In order to solve this problem, a backward framework is proposed which is composed of two different stages. The first one consists of two linear predictors devoted to improve the source separation, whitening the input signals. Their coefficients are calculated applying the LMS algorithm, minimizing the mean squared errors between the predicted signals and the output of the separation network. The second stage is formed by decoupling filters that have to be blindly estimated imposing an independence criterion to the outputsPeer Reviewe

Blind wideband source separation

This paper deals with the general problem of separating two independent wideband sources when they are mixed by unknown filters. In order to solve this problem, a backward framework is proposed which is composed of two different stages. The first one consists of two linear predictors devoted to improve the source separation, whitening the input signals. Their coefficients are calculated applying the LMS algorithm, minimizing the mean squared errors between the predicted signals and the output of the separation network. The second stage is formed by decoupling filters that have to be blindly estimated imposing an independence criterion to the outputsPeer Reviewe

Differences in tetracycline resistance determinant carriage among Shigella flexneri and Shigella sonnei are not related to different plasmid Inc-type carriage

Objectives: The aim of this study was to establish the prevalence of the most common molecular mechanisms involved in tetracycline resistance as well as their relationship with plasmid incompatibility (Inc) groups in a collection of Shigella spp. causing traveller’s diarrhoea. Methods: Tetracycline susceptibility was established in 187 Shigella spp. (74 Shigella flexneri and 113 Shigella sonnei), of which 153 isolates were recovered as a confirmed cause of traveller’s diarrhoea. The prevalence of the tet(A), tet(B) and tet(G) genes was analysed by PCR. Eighteen plasmid Inc groups was determined in a subset of 59 isolates. Results: Among 154 tetracycline-resistant isolates, 122 (79.2%) harboured at least tet(A) or tet(B). The tet(B) gene was the most frequently detected, being present in 70 isolates (45.5%), whilst tet(A) was detected in 57 isolates (37.0%). The tet(G) gene was present in only 11 (7.2%) isolates. Moreover, the tet(A) gene was more frequent in S. sonnei (P = 0.0007), whilst the tet(B) gene was more frequent in S. flexneri (P < 0.0001). Plasmids belonging to Inc group B (P < 0.05) were significantly more frequent among S. flexneri, whilst those belonging to groups K, FIC and FIIA (P < 0.05) were preferentially detected among S. sonnei. Conclusion: The prevalence of the tet(A) and tet(B) genes differed between S. sonnei and S. flexneri. Moreover, the prevalence of plasmid Inc groups in S. flexneri and S. sonnei differed. However, no relationship was found between the two phenomena